Policy Updates Prior AuthorizationMedicare AdvantageSeptember 24, 2024

Prior authorization requirement changes

Effective February 1, 2025

Effective February 1, 2025, prior authorization (PA) requirements will change for the following code(s). The medical code(s) listed below will require PA by Anthem for Medicare Advantage members. Federal and state law, as well as state contract language and Centers for Medicare & Medicaid Services guidelines, including definitions and specific contract provisions/exclusions take precedence over these precertification rules and must be considered first when determining coverage. Non‑compliance with new requirements may result in denied claims.

Prior authorization requirements will be added for the following code(s):

Code

Code description

0456U

Autoimmune (rheumatoid arthritis), next-generation sequencing (NGS), gene expression testing of 19 genes, whole blood, with analysis of anti-cyclic citrullinated peptides (CCP) levels, combined with sex, patient global assessment, and body mass index (BMI), algorithm reported as a score that predicts nonresponse to tumor necrosis factor inhibitor (TNFi) therapy
PrismRA®, Scipher Medicine®, Scipher Medicine®

0459U

β-amyloid (Abeta42) and total tau (tTau), electrochemiluminescent immunoassay (ECLIA), cerebral spinal fluid, ratio reported as positive or negative for amyloid pathology
Elecsys® Total Tau CSF (tTau) and β-Amyloid (1-42) CSF II (Abeta 42) Ratio, Roche Diagnostics Operations, Inc (US owner/operator)

0468U

Hepatology (nonalcoholic steatohepatitis [NASH]), miR-34a5p, alpha 2-macroglobulin, YKL40, HbA1c, serum and whole blood, algorithm reported as a single score for NASH activity and fibrosis
NASHnext™ (NIS4™), Labcorp, Labcorp

J0687

Injection, cefazolin sodium (WG Critical Care), not therapeutically equivalent to J0690, 500 mg

J0688

Injection, cefazolin sodium (hikma), not therapeutically equivalent to j0690, 500 mg

J0689

Injection, cefazolin sodium (baxter), not therapeutically equivalent to j0690, 500 mg

J0744

Injection, ciprofloxacin for intravenous infusion, 200 mg

J2183

Injection, meropenem (WG Critical Care), not therapeutically equivalent to J2185, 100 mg

J2184

Injection, meropenem (B. Braun), not therapeutically equivalent to J2185, 100 mg

J2281

Injection, moxifloxacin (Fresenius Kabi), not therapeutically equivalent to J2280, 100 mg

Not all PA requirements are listed here. Detailed PA requirements are available to providers on anthem.com/medicareprovider on the Resources tab or for contracted providers by accessing Availity.com. Providers may also call Provider Services at the number on the back of the patient’s member ID card for assistance with PA requirements.

UM AROW #: A2024M2186

Anthem Blue Cross and Blue Shield is the trade name of Anthem Health Plans of New Hampshire, Inc. HMO plans are administered by Anthem Health Plans of New Hampshire, Inc. and underwritten by Matthew Thornton Health Plan, Inc. Independent licensees of the Blue Cross Blue Shield Association. Anthem is a registered trademark of Anthem Insurance Companies, Inc.

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PUBLICATIONS: November 2024 Provider Newsletter