As a reminder, effective November 1, 2021, EnrollSafe will replace CAQH Enrollhub as the electronic funds transfer (EFT) enrollment portal for Anthem Blue Cross (Anthem) providers. As of November 1, 2021, CAQH Enrollhub will no longer offer EFT enrollment to new users.   CAQH Enrollhub is the only CAQH tool being decommissioned.  All other CAQH tools will not be impacted.


Benefits of EFT


Not only is receiving your payment more convenient, so is signing up for EFT.  When you sign up for EFT through EnrollSafe, the new enrollment portal, you’ll receive your payments up to seven days sooner than through the paper check method. What’s more, it’s easier to reconcile your direct deposits.


Secure and available 24-hours a day – EnrollSafe


Beginning November 1, 2021, if you need to make changes to an existing EFT enrollment or create a new first-time account, log onto the EnrollSafe enrollment hub at to enroll in EFT.  Once you have completed registration, you’ll be directed through the EnrollSafe secure portal to the enrollment page, where you’ll provide the required information to receive direct payment deposits.


Already enrolled in EFT through CAQH Enrollhub?


Please note if you’re already enrolled in EFT through CAQH Enrollhub, no action is needed unless making changes. Your EFT enrollment information will not change as a result of the new enrollment hub.


If you have changes to make, after October 31, 2021, use EnrollSafe to update your account.


Electronic remittance advice (ERA) makes reconciling your EFT payments easy and paper-free


Now that you are enrolled in EFT, using the digital ERA is the very best way to reconcile your deposits – securely and safely. You’ll be issued a trace number with your EFT deposit that matches up with your ERA on Availity.


ERAs can be retrieved directly from Availity.  Log onto Availity and select Claims and Payments > Send and Receive EDI Files > Received Files folder.  When using a clearinghouse or billing service, they will supply the 835 ERA for you.  You also have the option to view or download a copy of the Remittance Advice under Payer Spaces > Remittance Inquiry tool.

Contact information

Electronic Remittance Advice (ERA), Electronic Funds Transfer (EFT) registration

 and contact information

Type of transaction:

How to register, update, or cancel:

For registration related questions, contact:

To resolve issues after registration, contact:

EFT only

Use EnrollSafe

EnrollSafe help desk at


EnrollSafe help desk at


ERA (835) only

Use Availity

Availity Support


Availity at 1-800-282-4548


NOTE – Providers should allow up to 10 business days for ERA enrollment processing.


Featured In:
October 2021 Anthem Blue Cross Provider News - California