Policy Updates Medical Policy & Clinical GuidelinesMedicaid Managed CareFebruary 6, 2025

Clinical Criteria updates

Effective March 10, 2025

The Pharmacy and Therapeutic (P&T) Committee approved the following Clinical Criteria applicable to the medical drug benefit for Anthem. These policies were developed, revised, or reviewed to support clinical coding edits.

Visit Clinical Criteria to search for specific policies. For questions or additional information, use this email.

Please see the explanation/definition for each category of Clinical Criteria below:

  • New: newly published criteria
  • Revised: addition or removal of medical necessity requirements, new document number

Please share this notice with other members of your practice and office staff.

Please note:

  • The Clinical Criteria listed below apply only to the medical drug benefits contained within the member’s medical policy. This does not apply to pharmacy services.
  • This notice is meant to inform the provider of new or revised criteria that have been adopted by Anthem only. It does not include details regarding any authorization requirements. Authorization rules are communicated via a separate notice.

Effective date

Clinical Criteria number

Clinical Criteria title

New or revised

March 10, 2025

CC-0266

Rytelo (imetelstat)

New

March 10, 2025

CC-0156

Reblozyl (luspatercept)

Revised

March 10, 2025

CC-0244

Columvi (glofitamab-gxbm)

Revised

March 10, 2025

CC-0124

Keytruda (pembrolizumab)

Revised

March 10, 2025

CC-0104

Levoleucovorin Agents

Revised

March 10, 2025

CC-0182

Iron Agents

Revised

March 10, 2025

CC-0197

Jemperli (dostarlimab-gxly)

Revised

March 10, 2025

CC-0247

Beyfortus (nirsevimab)

Revised

March 10, 2025

CC-0082

Onpattro (patisiran)

Revised

March 10, 2025

CC-0217

Amvuttra (vulrisiran)

Revised

March 10, 2025

CC-0084

Tegsedi (inotersen)

Revised

March 10, 2025

CC-0209

Leqvio (inclisiran)

Revised

March 10, 2025

CC-0193

Evkeeza (evinacumab)

Revised

March 10, 2025

CC-0027

Denosumab

Revised

March 10, 2025

CC-0019

Zoledronic Acid

Revised

March 10, 2025

CC-0246

Rystiggo (rozanolixizumab-noli)

Revised

March 10, 2025

CC-0207

Vyvgart (efgartigimod alfa-fcab) and Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-gvfc)

Revised

March 10, 2025

CC-0028

Benlysta (belimumab)

Revised

March 10, 2025

CC-0127

Darzalex (daratumumab) and Darzalex Faspro (daratumumab and hyaluronidase-fihj)

Revised

March 10, 2025

CC-0121

Gazyva (obinutuzumab)

Revised

March 10, 2025

CC-0242

Epkinly (epcoritamab-bysp)

Revised

March 10, 2025

CC-0130

Imfinzi (durvalumab)

Revised

March 10, 2025

CC-0158

Enhertu (fam-trastuzumab deruxtecan-nxki)

Revised

March 10, 2025

CC-0048

Spinraza (nusinersen)

Revised

March 10, 2025

CC-0003

Immunoglobulins

Revised

March 10, 2025

CC-0058

Sandostatin and Sandostatin LAR (Octreotide) / Octreotide Agents

Revised

Anthem Blue Cross and Blue Shield Medicaid is the trade name of Community Insurance Company. Independent licensee(s) of the Blue Cross Blue Shield Association. Anthem is a registered trademark of Anthem Insurance Companies, Inc.

OHBCBS-CD-074703-24

PUBLICATIONS: March 2025 Provider Newsletter