Policy UpdatesMedicare AdvantageJune 2, 2025

Clinical Criteria updates

Effective July 6, 2025


Summary: The Pharmacy and Therapeutics (P&T) Committee approved the following Clinical Criteria applicable to the medical drug benefit for Anthem. These policies were developed, revised, or reviewed to support clinical coding edits.

Visit Clinical Criteria to search for specific policies. For questions or additional information, use this email.

Please see the explanation/definition for each category of Clinical Criteria below:

  • New: newly published criteria
  • Revised: addition or removal of medical necessity requirements, new document number

Please share this notice with other members of your practice and office staff.

Please note:

  • The Clinical Criteria listed below applies only to the medical drug benefits contained within the member’s medical plan. This does not apply to pharmacy services.
  • This notice is meant to inform the provider of new or revised criteria that has been adopted by Anthem only. It does not include details regarding any authorization requirements. Authorization rules are communicated via a separate notice.

Effective date

Clinical Criteria number

Clinical Criteria title

Status

July 6, 2025

CC-0278

Unloxcyt (cosibelimab-ipdl)

New

July 6, 2025

CC-0279

Datroway (datopotamab deruxtecan-dlnk)

New

July 6, 2025

CC-0280

Grafapex (treosulfan)

New

July 6, 2025

CC-0281

Opdivo Qvantig (nivolumab hyaluronidase-nvhy)

New

July 6, 2025

CC-0128

Atezolizumab (Tecentriq, Tecentriq Hybreza)

Revised

July 6, 2025

CC-0158

Enhertu (fam-trastuzumab deruxtecan-nxki)

Revised

July 6, 2025

CC-0125

Opdivo (nivolumab)

Revised

July 6, 2025

CC-0119

Yervoy (ipilimumab)

Revised

July 6, 2025

CC-0099

Abraxane (paclitaxel, protein bound)

Revised

July 6, 2025

CC-0093

Docetaxel (Docivyx)

Revised

July 6, 2025

CC-0118

Radioimmunotherapy and Somatostatin Receptor Targeted Radiotherapy (Azedra, Lutathera, Pluvicto, Zevalin)

Revised

July 6, 2025

CC-0123

Cyramza (ramucirumab)

Revised

July 6, 2025

CC-0121

Gazyva (obinutuzumab)

Revised

July 6, 2025

CC-0122

Arzerra (ofatumumab)

Revised

July 6, 2025

CC-0232

Lunsumio (mosunetuzumab-axgb)

Revised

July 6, 2025

CC-0109

Zaltrap (ziv-aflibercept)

Revised

July 6, 2025

CC-0135

Melanoma Vaccines

Revised

July 6, 2025

CC-0126

Blincyto (blinatumomab)

Revised

July 6, 2025

CC-0132

Mylotarg (gemtuzumab ozogamicin)

Revised

July 6, 2025

CC-0097

Vidaza (azacitidine)

Revised

July 6, 2025

CC-0129

Bavencio (avelumab)

Revised

July 6, 2025

CC-0110

Perjeta (pertuzumab)

Revised

July 6, 2025

CC-0108

Halaven (eribulin)

Revised

July 6, 2025

CC-0149

Select Clotting Agents for Bleeding Disorders

Revised

July 6, 2025

CC-0262

Tevimbra (tislelizumab-jsgr)

Revised

July 6, 2025

CC-0061

Gonadotropin Releasing Hormone (GnRH) Analogs for the Treatment of Non-Oncologic

Revised

July 6, 2025

CC-0026

Testosterone Injectable

Revised

July 6, 2025

CC-0008

Subcutaneous Hormonal Implants

Revised

July 6, 2025

CC-0015

Infertility and HCG Agents

Revised

July 6, 2025

CC-0033

Xolair (omalizumab)

Revised

July 6, 2025

CC-0043

Monoclonal Antibodies to Interleukin-5

Revised

July 6, 2025

CC-0029

Dupixent (dupilumab)

Revised

July 6, 2025

CC-0269

Nemluvio (nemolizumab-ilto)

Revised

July 6, 2025

CC-0267

Ebglyss (lebrikizumab-lbkz)

Revised

July 6, 2025

CC-0208

Adbry (tralokinumab)

Revised

July 6, 2025

CC-0086

Spravato (esketamine) Nasal Spray

Revised

July 6, 2025

CC-0050

Monoclonal Antibodies to Interleukin-23

Revised

July 6, 2025

CC-0063

Ustekinumab Agents (Stelara, Selarsdi, Imuldosa, Pyzchiva, Otulfi, Steqeyma, Wezlana, Yesintek)

Revised

July 6, 2025

CC-0261

Winrevair (sotatercept-csrk)

Revised

July 6, 2025

CC-0010

Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Inhibitors

Revised

July 6, 2025

CC-0209

Leqvio (inclisiran)

Revised

July 6, 2025

CC-0002

Colony Stimulating Factor Agents

Revised

July 6, 2025

CC-0003

Immunoglobulins

Revised

Anthem Blue Cross and Blue Shield is the trade name of Rocky Mountain Hospital and Medical Service, Inc. HMO products underwritten by HMO Colorado, Inc., dba HMO Nevada. Independent licensee(s) of the Blue Cross Blue Shield Association. Anthem is a registered trademark of Anthem Insurance Companies, Inc.

CPN81379, MULTI-BCBS-CR-082344-25