Material adverse change (MAC)


Anthem Blue Cross and Blue Shield (Anthem) entered into a pilot program to accept electronic medical attachment from VYNE Medical. This pilot program expired and the grace period for submitting electronic attachments through VYNE Medical has expired.

On May 1, 2022, attachments submitted through VYNE Medical will no longer be accessible by Anthem.  Thus, you may not submit attachments for claims you are submitting to Anthem through VYNE.
The alternative for submitting medical attachments is through Electronic Data Interchange (EDI) or through This will ensure your medical attachments re appropriately received and aligned to the correct claim.


If you are not enrolled in and EDI, the process is simple. Log onto to go through the step-by-step process for enrollment. For information about how to enroll in EDI, use this convenient Batch EDI Standard Companion Guide after logging onto


For more information about enrolling in Availity, contact their client services department at

800-282-4548, Monday through Friday, 8:00 a.m. to 8:00 p.m. ET.



Featured In:
February 2022 Anthem Provider News - Nevada