Policy Updates Medical Policy & Clinical GuidelinesCommercialMay 31, 2023

Medical Policies and Clinical Guidelines Updates — June 2023

The following Anthem Blue Cross and Blue Shield (Anthem) medical policies and clinical guidelines were reviewed on February 16, 2023, for Indiana, Kentucky, Missouri, Ohio, and Wisconsin.

To view medical policies and utilization management guidelines, go to anthem.com > select Providers > select your state > under Provider Resources > select Policies, Guidelines & Manuals.

To help determine if prior authorization (PA) is needed for Anthem members, go to anthem.com > select Providers > select your state > under Claims > select Prior Authorization. You can also call the prior authorization phone number on the back of the member’s ID card.

To view medical policies and utilization management guidelines applicable to members enrolled in the Blue Cross and Blue Shield Service Benefit Plan (commonly referred to as the Federal Employee Program® (FEP)), please visit fepblue.org > Policies & Guidelines.

Below are the new medical policies and/or clinical guidelines that have been approved.
* Denotes PA required

Policy/guideline

Information

Effective date

*MED.00145

Digital Therapy Devices for Treatment of Amblyopia

Digital therapy devices for treatment of amblyopia are considered INV&NMN
Added existing CPT® Category III codes 0687T, 0688T, 0704T, 0705T, 0706T; considered INV&NMN

September 1, 2023



Below are the current clinical guidelines and/or medical policies we reviewed, and updates were approved.
* Denotes PA required

Policy/guideline

Information

Effective date

CG-GENE-19

Measurable Residual Disease Assessment in Lymphoid Cancers Using Next Generation Sequencing

Added new CPT PLA code 0364U for clonoSEQ (was NOC code); MN when criteria are met

September 1, 2023


*CG-MED-73

Hyperbaric Oxygen Therapy (Systemic/Topical)

Removed diagnosis code L88 (not applicable)
Adding to Anthem PA

September 1, 2023

CG-SURG-106

Venous Angioplasty with or without Stent Placement or Venous Stenting Alone

Added new MN criterion for idiopathic intracranial hypertension (IIH)
CPT codes 61630, 61635 and associated ICD-10-PCS codes considered MN for IIH diagnosis when criteria are met (were NMN)

September 1, 2023

*CG-SURG-97 

Cardioverter Defibrillators

Removed code 00534 for associated anesthesia, not addressed

April 12, 2023

*GENE.00049 

Circulating Tumor DNA Panel Testing (Liquid Biopsy)


Added new MN statement for panels that assess tumor mutation burden (TMB) and revised INV&NMN statement.
CPT PLA codes 0239U (Foundation One Liquid CDx) and 0326U (Guardant360®) considered MN when criteria are met (previously INV&NMN); added new CPT PLA code 0368U effective 4/1/2023 for ColoScape™ Colorectal Cancer Detection, considered INV&NMN

September 1, 2023

*GENE.00054 

Paired DNA and Messenger RNA (mRNA) Genetic Testing to Detect, Diagnose and Manage Cancer

Added CPT PLA codes 0130U, 0131U, 0132U, 0134U, 0135U previously addressed in GENE.00052; considered INV&NMN

September 1, 2023

*LAB.00039

Pooled Antibiotic Sensitivity Testing

Added new CPT PLA codes 0372U, 0374U for genitourinary antibiotic resistance tests, considered INV&NMN

September 1, 2023

*MED.00101

Physiologic Recording of Tremor using Accelerometer(s) and Gyroscope(s)

Added existing CPT Category III code 0778Tconsidered INV&NMN

April 12, 2023

*MED.00135

PGene Therapy for Hemophilia

Added new HCPCS code J1411 effective 4/1/2023 for Hemgenix, MN when criteria are met (NOC codes no longer applicable for Hemgenix)

September 1, 2023

*SURG.00011

Allogeneic, Xenographic, Synthetic, Bioengineered, and Composite Products for Wound Healing and Soft Tissue Grafting

• Revised MN statement to include SimpliDerm for breast reconstruction

• Revised MN statement to include Kerecis and TheraSkin for diabetic foot ulcers

• Revised MN statement to include AmnioBand for venous stasis ulcers

• Revised MN statement to include OviTex for complex abdominal wall wounds

• Revised formatting in several MN statements

• Revised NMN statement to align with revisions to MN statements

• Added new products to the INV&NMN statement

HCPCS code Q4158 for Kerecis considered MN when criteria are met (was Inv&NMN), code Q4151 for AmnioBand considered MN for additional diagnoses when criteria are met, OviTex & SimpliDerm (NOC codes) considered MN when criteria are met; added new HCPCS codes A2019, A2020, A2021, Q4265, Q4266, Q4267, Q4268, Q4269, Q4270, Q4271 for products considered INV&NMN

September 1, 2023

*CG-GENE-13

Genetic Testing for Inherited Diseases

Added new CPT PLA code 0378U effective April 1, 2023, for UCGSL RFC1 Repeat Expansion Test, and gene RFC1 to table; considered NMN

September 1, 2023

*DME.00048

Virtual Reality-Assisted Therapy Systems

Added new HCPCS code E1905 effective 4/1/2023 for VR cognitive behavioral therapy device such as RelieVRx; considered INV&NMN
Adding to Anthem PA

September 1, 2023

*SURG.00103

Intraocular Anterior Segment Aqueous Drainage Devices (without extraocular reservoir)

Revised MN and INV&NMN Position Statements to address iStent infinite Trabecular Micro-Bypass Stent System, model iS3

April 12, 2023

*DME.00049

External Upper Limb Stimulation for the Treatment of Tremors

Revised descriptor for HCPCS code K1019
Adding to Anthem PA

September 1, 2023

*GENE.00010

Panel and other Multi-Gene Testing for Polymorphisms to Determine Drug-Metabolizer Status

Added new CPT PLA code 0380U for Personalized RX; considered INV&NMN

September 1, 2023

*GENE.00052 

Whole Genome Sequencing, Whole Exome Sequencing, Gene Panels, and Molecular Profiling

Added new CPT PLA code 0379U for a molecular profiling panel, MN when criteria are met; removed codes 0130U, 0131U, 0132U, 0134U, 0135U that will be addressed in GENE.00054

September 1, 2023

LAB.00003 

In Vitro Chemosensitivity Assays and In Vitro Chemoresistance Assays

Removed CPT PLA codes 0324U, 0325U

March 29, 2023

*LAB.00026 

Systems Pathology Testing for Prostate Cancer

Added new CPT PLA code 0376U for Artera AI Prostate Test; considered INV&NMN

September 1, 2023

*LAB.00031

Advanced Lipoprotein Testing

Added new CPT PLA code 0377U for Liposcale®; considered INV&NMN

September 1, 2023

*SURG.00010

Treatments for Urinary Incontinence

Added new HCPCS codes A4341, A4342 for inFlow device and supplies, considered INV&NMN (NOC code A4335 no longer applicable)

September 1, 2023

*SURG.00158 

Implantable Peripheral Nerve Stimulation Devices as a Treatment for Pain

Added new HCPCS code L8678 for stimulator supplies (patch), considered INV&NMN when used with PNS pain device; also added existing code L8681 for programming device used with PNS

September 1, 2023

*DME.00011

Electrical Stimulation as a Treatment for Pain and Other Conditions: Surface and Percutaneous Devices

Adding to Anthem PA

September 1, 2023

*DME.00012

Intrapulmonary Percussive Ventilation Devices

Adding to Anthem PA

September 1, 2023

*DME.00022

Functional Electrical Stimulation (FES); Threshold Electrical Stimulation (TES)

Adding to Anthem PA

September 1, 2023

*DME.00038

Static Progressive Stretch (SPS) and Patient-Actuated Serial Stretch (PASS) Devices

Adding to Anthem PA

September 1, 2023

*DME.00042

Electronic Positional Devices for the Treatment of Obstructive Sleep Apnea

Adding to Anthem PA

September 1, 2023

*MED.00122

Wilderness Programs

Adding to Anthem PA

September 1, 2023

*OR-PR.00005 

Upper Extremity Myoelectric Orthoses

Adding to Anthem PA

September 1, 2023

*OR-PR.00006 

Powered Robotic Lower Body Exoskeleton Devices

Adding to Anthem PA

September 1, 2023

*SURG.00084 

Implantable Middle Ear Hearing Aids

Adding to Anthem PA

September 1, 2023

*SURG.00118 

Bronchial Thermoplasty

Adding to Anthem PA

September 1, 2023

*SURG.00121 

Transcatheter Heart Valve Procedures

Adding to Anthem PA

September 1, 2023

*SURG.00129 

Oral, Pharyngeal and Maxillofacial Surgical Treatment for Obstructive Sleep Apnea or Snoring

Adding to Anthem PA

September 1, 2023

*TRANS.00004 

Cell Transplantation (Mesencephalic, Adrenal-Brain and Fetal Xenograft)

Adding to Anthem PA

September 1, 2023

*TRANS.00010 

Autologous and Allogeneic Pancreatic Islet Cell Transplantation

Adding to Anthem PA

September 1, 2023

*TRANS.00035 

Therapeutic use of Stem Cells, Blood, and Bone Marrow Products

Adding to Anthem PA

September 1, 2023

MULTI-BCBS-CM-024768-23

PUBLICATIONS: June 2023 Provider Newsletter