In November 2021, Anthem Blue Cross and Blue Shield transitioned from CAQH Enrollhub to EnrollSafe* as the preferred vendor for EFT (electronic funds transfer). If you are not already enrolled for electronic payments, follow the instructions below to do so.


Sign up for EnrollSafe

Log onto the EnrollSafe enrollment hub at to enroll in EFT. Once you have completed registration, you’ll be directed through the EnrollSafe secure portal to the enrollment page. There, you’ll provide the required information to receive direct payment deposits. There is no fee to register for EFT via EnrollSafe.


For registration related questions, contact the EnrollSafe help desk at 877-882-0384, available Monday through Friday, 9 a.m. to 8 p.m. ET, except on public and/or bank holidays. You can also email EnrollSafe at


If you have additional questions, please contact Provider Services.

* EnrollSafe is a tool developed by Zelis Payments, an independent organization offering electronic fund transfer services on behalf of Anthem Blue Cross and Blue Shield.



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Enroll through EnrollSafe to be paid via EFT - Kentucky